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JCO Oncol Pract ; 16(11): e1282-e1290, 2020 11.
Article in English | MEDLINE | ID: covidwho-1110049

ABSTRACT

PURPOSE: Patients with cancer are at higher risk for contracting the COVID-19 infection and are more likely to have higher morbidity and mortality. This is a big challenge for oncology teams that have to treat patients to avoid contamination by SARS-CoV-2. The aim of the current work is to present oncology pharmacy practice guidelines during the COVID-19 pandemic to secure the pharmaceutical care of patients with cancer. METHODS: The bureau of the French Society for Oncology Pharmacy proposed these recommendations according to the French High Authority of Health following the Guidelines of Good Practice, slightly modified according to the pandemic crisis situation. These guidelines were developed by a working group of 7 experts in oncology pharmacy practice. Furthermore, the guidelines were assessed by 31 independent reviewers. RESULTS: One hundred percent of reviewers approved the guidelines and 90% of them suggested some improvements. The final version incorporates the best comments and consists of 26 recommendations organized in 8 different sections. CONCLUSION: These guidelines allow secure pharmaceutical management of patients with cancer during the COVID-19 pandemic.


Subject(s)
COVID-19 Drug Treatment , Neoplasms/drug therapy , Pandemics , SARS-CoV-2/pathogenicity , COVID-19/complications , COVID-19/epidemiology , COVID-19/virology , Female , France/epidemiology , Humans , Male , Medical Oncology/trends , Neoplasms/complications , Neoplasms/epidemiology , Neoplasms/virology , Pharmaceutical Services , Pharmacies/trends , Practice Guidelines as Topic , SARS-CoV-2/drug effects
3.
Cancer Treat Rev ; 88: 102063, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-634600

ABSTRACT

The Coronavirus disease (COVID-19) pandemic is disrupting our health environment. As expected, studies highlighted the great susceptibility of cancer patients to COVID-19 and more severe complications, leading oncologists to deeply rethink patient cancer care. This review is dedicated to the optimization of care pathways and therapeutics in cancer patients during the pandemic and aims to discuss successive issues. First we focused on the international guidelines proposing adjustments and alternative options to cancer care in order to limit hospital admission and cytopenic treatment in cancer patients, most of whom are immunocompromised. In addition cancer patients are prone to polypharmacy, enhancing the risk of drug-related problems as adverse events and drug-drug interactions. Due to increased risk in case of COVID-19, we reported a comprehensive review of all the drug-related problems between COVID-19 and antineoplastics. Moreover, in the absence of approved drug against COVID-19, infected patients may be included in clinical trials evaluating new drugs with a lack of knowledge, particularly in cancer patients. Focusing on the several experimental drugs currently being evaluated, we set up an original data board helping oncologists and pharmacists to identify promptly drug-related problems between antineoplastics and experimental drugs. Finally additional and concrete recommendations are provided, supporting oncologists and pharmacists in their efforts to manage cancer patients and to optimize their treatments in this new era related to COVID-19.


Subject(s)
Coronavirus Infections/drug therapy , Coronavirus Infections/immunology , Medical Oncology/standards , Neoplasms/drug therapy , Neoplasms/immunology , Pharmacy/standards , Pneumonia, Viral/drug therapy , Pneumonia, Viral/immunology , Antineoplastic Agents/administration & dosage , Antineoplastic Agents/adverse effects , Betacoronavirus/isolation & purification , COVID-19 , Clinical Trials as Topic/methods , Clinical Trials as Topic/standards , Coronavirus Infections/virology , Humans , Medical Oncology/methods , Neoplasms/virology , Pandemics , Pharmacy/methods , Pneumonia, Viral/virology , Practice Guidelines as Topic , SARS-CoV-2
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